THE MECHANISM OF ACTION OF METABOLIC CYTOPROTECTOR TRIMETAZIDINE IN ACUTE ISCHEMIA-REPERFUSION INJURY

The review presents, as the classical data on the mechanism of action of metabolic cytoprotector trimetazidine in acute ischemia/reperfusion injury associated with a partial inhibition of the oxidation of KK@ALL long chain fatty acids and increased metabolism of pyruvate, as well as new concepts of reducing the level of oxidative stress, reduction

Maintaining public trust, legitimacy, and credibility in a constantly evolving society has proven challenging for police in the 21st century.Rising public concerns regarding police accountability are driving the need to advance the paradigm of policing by reassessing the organizational structure of law enforcement in Canada.Supported by research id